Endocrine Abstracts

Introduction: The effects of dopamine (DA), serotonin (5-HT), histamine (HA) adrenaline (ADR), noradrenaline (NADR) and K+ administration on vasopressin (VP) secretion were studied in 13–14 days cultures of rat neurohypophyseal (NH) cells, and it was examined whether orexin (ORX) can modify the VP release enhancement induced by these monoaminergic compounds.Methods: An enzymatic dissociation technique was used to prepare the rat NH cell c...

The endocrine disruptor compounds (EDC) (e.g. chlorobenzenes (ClB), phenurone (PU), monurone (MU), diurone (DU)) are accumulative, lipophilic, chemical pollutants that can disturb the homeostatic balance and exert tumorigenic effects. The aim of the present study was to investigate the effects of EDCs on the adrenocorticotropic hormone (ACTH) and prolactin (Prl) release in primary cell cultures derived from rat normal adenohypophysis and prolactinoma.The...